The best way to fix this problem is to fix it yourself.
Skyrim uses a game engine called Gamebryo that is probably more than a decade old, starting with the release of Morrowind in Foremost among these problems is the fact that Gamebryo is completely and utterly useless when it comes to garbage collection the process of cleaning up dead references and objects in an environment.
I am told I am pretty good at save cleaning, so I will leave you with this guide on how to clean your saves.
It also translates EFF commands follow, wait, relax, etc. Even if forced to become a follower again, she will continue to walk home instead of following you. My mod fixes this by having a plugin remove the problematic dialogue entries. Because of this, Serana, unlike most NPCs in the game, will basically tell you to go fuck yourself if you ask her to come with you when you already have a follower. Skyrim was coded with the assumption that the player would only have one follower at a time. Unfortunately, this AI also clashes with mods like Extensible Follower Framework, which enable you to have more than one follower at a time. Pb_user_ / Octo/ Skyrim save cleaner / comments
